Katja et.al., Dewa Gede (2017) Jurnal Ilmiah Kimia Molekul. Molekul, 12 (1). pp. 1-108. ISSN 2503-0310
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Abstract
Three cytotoxic steroids, stigmasterol (1), stigmast-5-en-3-ol (2) and -sitosterol-3-O-acetate (3) were isolated from the stem bark of Chisocheton cumingianus. The chemical structures of those compounds were identified based on spectroscopic data and by comparison with those data previously reported. All of the compounds isolated were evaluated for their cytotoxic effects against P-388 murine leukemia cells in vitro. Compounds 1-3 showed cytotoxicity activity against P-388 murine leukemia cells with IC50 values of 12.4,60.8, and ˃ 100 g/mL, respectively.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | C. cumingianus, Chisocheton, cytotoxic activity, Meliaceae, Steroids |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Stikes Borneo Cendekia Medika |
| Date Deposited: | 21 Oct 2020 01:40 |
| Last Modified: | 02 Nov 2020 04:17 |
| URI: | http://repository.stikesbcm.ac.id/id/eprint/58 |
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