Biotechnology Research & Innovation

Shankar, Saranya (2018) Biotechnology Research & Innovation. Biotechnology Research & Innovation, 2 (1). pp. 1-90.

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The present study aims to analyze the antimicrobial, antioxidant and antiinflammatory activity of Dracaena mahatma leaf extract. Qualitative phytochemical screening of leaf powder confirmed the presence of tannins, alkaloids, phenols, terpenoids, sterols, triterpenes and anthraquinone glycosides. GC-MS analysis of methanolic extract suggested the presence of 2 unknown compounds and 8 known phytochemicals, of which benzene-(1,6-hexanediylidene)tetrakis constituted a maximum percentage of the crude extract. The total phenolic content of the crude extract was found to be 32.9 ± 0.002GAE/g. Crude extract demonstrated 90% antioxidant activity in DPPH assay at 100 g/ml concentration and also emonstrated significant antioxidant activity in FRAP assay at 100 g/ml concentration. The crude extract did not show any antagonism against fungal pathogens Aspergillus niger and Aspergillus flavus. Crude extract demonstrated significant antibacterial activity against 5 studied pathogen, with the highest antagonism against Escherichia coli with a zone of inhibition of 22 mm at 10 mg/well concentration.

Item Type: Article
Uncontrolled Keywords: Ornamental plant;Dracaena mahatma;Antibacterial activity;Gas chromatography-massspectrometry;Antioxidant;Anti-inflammatory
Subjects: R Medicine > R Medicine (General)
Depositing User: Stikes Borneo Cendekia Medika
Date Deposited: 21 Oct 2020 04:59
Last Modified: 02 Nov 2020 04:03

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